Mouse goes to sleep?

[Jeffrey Ross]

System is Fedora 10 x86_64, the mouse is a Micro$oft wireless Laser 
Mouse 5000. 

The mouse occasionally stops responding for one or two seconds and then 
continues like nothing happened.   There are no messages in the logfiles 
related to the mouse and the the keyboard which is also USB does not 
have any issues.

The desktop is Gnome and I all currently available patches/updates have 
been installed.

Any suggestions would be appreciated.

Thanks, Jeff