With JBoss AOP you can change advice and interceptor bindings at runtime. You can unregister existing bindings, and hot deploy new bindings if the given points have been instrumented. There is also a runtime API for adding advice bindings at runtime. Getting an instance of org.jboss.aop.AspectManager.instance(), you can add your binding.

AdviceBinding binding = new AdviceBinding("execution(POJO->new(..))", null);
binding.addInterceptor(SimpleInterceptor.class);
AspectManager.instance().addBinding(binding);

First, you allocated an AdviceBinding passing in a pointcut expression. Then you add the interceptor via its class and then add the binding through the AspectManager. When the binding is added the AspectManager will iterate through ever loaded class to see if the pointcut expression matches any of the joinpoints within those classes.